diff --git a/drivers/gpu/drm/amd/amdgpu/gfx_v9_0.c b/drivers/gpu/drm/amd/amdgpu/gfx_v9_0.c
index ef430f285472..5f4805e4d04a 100644
--- a/drivers/gpu/drm/amd/amdgpu/gfx_v9_0.c
+++ b/drivers/gpu/drm/amd/amdgpu/gfx_v9_0.c
@@ -2633,7 +2633,14 @@ static void gfx_v9_0_wait_for_rlc_serdes(struct amdgpu_device *adev)
 static void gfx_v9_0_enable_gui_idle_interrupt(struct amdgpu_device *adev,
 					       bool enable)
 {
-	u32 tmp = RREG32_SOC15(GC, 0, mmCP_INT_CNTL_RING0);
+	u32 tmp;
+
+	/* don't toggle interrupts that are only applicable
+	 * to me0 pipe0 on AISCs that have me0 removed */
+	if (!adev->gfx.num_gfx_rings)
+		return;
+
+	tmp= RREG32_SOC15(GC, 0, mmCP_INT_CNTL_RING0);
 
 	tmp = REG_SET_FIELD(tmp, CP_INT_CNTL_RING0, CNTX_BUSY_INT_ENABLE, enable ? 1 : 0);
 	tmp = REG_SET_FIELD(tmp, CP_INT_CNTL_RING0, CNTX_EMPTY_INT_ENABLE, enable ? 1 : 0);